Aviva Systems Biology provides an extensive collection of quality antibodies for research and diagnostic applications. Aviva currently offers antibodies to more than 7,000 different protein targets due to their high throughput antibody production, and releases more than 200 new antibodies every month. Aviva’s antibody collection includes those that are not commercially available elsewhere. The focus is key targets in areas of transcription, epigenetics and cell signaling, but antibodies are available in the following areas:
Nearly 8000 Transcription Factor Antibodies – Fully Characterized and Validated
Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Transcription factors can function downstream of signaling cascades triggered by biological (e.g. development, disease) or environmental (e.g. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Transcription factors can also function as oncogenes or tumor suppressors.
Aviva offers antibodies targeting different domains of transcription factors, including antibodies specific for post-translational modifications on transcription factors.
- Rabbit Polyclonal Antibody Production
- Mouse Monoclonal Antibody Production
- Peptide Synthesis
- Full-length Transcription Factor cDNA cloning
- Promoter-specific Oligo Design for ChIP Assay